Alice takes Claire along to try to find others, and as they are flying over various cities, they see people on the roof of an old prison, trying to be rescued. Claire has lost her memory, and has no idea who Alice is, so Alice has to restrain her in order to keep Claire from harming herself or Alice. The only Arcadia that she knows of is in Alaska, but when she arrives, all she finds is empty airplanes, and one survivor: Claire. Her diary gives the impression that she is giving herself someone to talk to, as well as leaving her story behind in case something happens to her. She explains her story at the beginning of the film through a video diary, because she is alone, and has found no one. Now, she is on her search for Arcadia, the one place on earth that is virus-free.
At the end of the previous movie, Alice has said good bye to her friends Claire and K-Mart, and has promised to see them again. Alice has escaped once again from death at the hands of the T-virus, and the walking dead it created.
He and Alice fight, and he gives her an antidote for the T-virus, basically rendering her purely human again. Alice is introduced to her nemesis for this movie, a man who has been also successfully bonded with the T-virus, giving him exceptional speed, strength and vision. Alice has created clones of herself, so that she can go to an Umbrella Corporation branch and try to take out the leaders of this evil corporation. The T-virus reanimates bodies, after they have died. Umbrella has been working with bioweapons, and has created the T-virus. At the beginning of Resident Evil: Afterlife, the audience is again introduced to Alice, a former security agent for the Umbrella Corporation.
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